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Article

Genomic loss of imprinting in first-trimester human placenta.

American journal of obstetrics and gynecology - 1 Apr 2010

Pozharny Yevgeniya, Lambertini Luca, Ma Yula, Ferrara Lauren, Litton Christian G, Diplas Andreas, Jacobs Adam R, Chen Jia, Stone Joanne L, Wetmur James, Lee Men-Jean

Abstract excerpt

OBJECTIVE: The purpose of this study was to investigate imprinting patterns in first-trimester human placentas. STUDY DESIGN: Using samples of 17 first-trimester and 14 term placentas from uncomplicated pregnancies, we assessed loss of imprinting (LOI) at the RNA level in a panel of 14 genes that are known to be imprinted in the placenta with the use of a quantitative allele-specific reverse transcriptase...

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Share to Epigenesis, Genetic
Share to Genomic Imprinting

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Pregnancy

Share to Pregnancy Trimester, First

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Identifiers

PMID: 20350649
DOI: 10.1016/j.ajog.2010.01.039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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