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Article

Genomic imprinting in the placenta

1 Jan 2006

Abstract excerpt

Genomic imprinting is an epigenetic mechanism that is important for the development and function of the extra-embryonic tissues in the mouse. Remarkably all the autosomal genes which were found to be imprinted in the trophoblast (placenta) only are active on the maternal and repressed on the paternal allele. It was shown for several of these genes that their paternal silencing is not dependent on DNA methylation,...

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PMID: 16575167
DOI: 10.1159/000090819

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