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Article

Transmission and cross-mating of high-level resistance Plasmodium falciparum dihydrofolate reductase haplotypes in The Gambia.

The American journal of tropical medicine and hygiene - 1 Apr 2010

Kheir Amani, Nwakanma Davis, Al-Gazali Aisha, Akbarova Yagut, Al-Saai Salma, Swedberg Göte, Babiker Hamza A

Abstract excerpt

A high-level pyrimethamine resistance Plasmodium falciparum lineage with triple dihydrofolate reductase (dhfr) mutations prevails across Africa. However, additional minority lineages were seen. We examined transmission success of mutant dhfr haplotypes among 22 children in The Gambia and 60 infected Anopheles gambiae mosquitoes fed on their blood. Additional polymorphic genes of the gametocyte-specific protein...

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Identifiers

PMID: 20348495
DOI: 10.4269/ajtmh.2010.09-0378
PMCID: PMC2844565

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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