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Identification of T. gondii epitopes, adjuvants, and host genetic factors that influence protection of mice and humans.

Vaccine - 21 May 2010

Tan Tze Guan, Mui Ernest, Cong Hua, Witola William H, Montpetit Alexandre, Muench Stephen P, Sidney John, Alexander Jeff, Sette Alessandro, Grigg Michael E, Maewal Ajesh, McLeod Rima

Abstract excerpt

Toxoplasma gondii is an intracellular parasite that causes severe neurologic and ocular disease in immune-compromised and congenitally infected individuals. There is no vaccine protective against human toxoplasmosis. Herein, immunization of L(d) mice with HF10 (HPGSVNEFDF) with palmitic acid moieties or a monophosphoryl lipid A derivative elicited potent IFN-gamma production from L(d)-restricted CD8(+) T cells in...

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Source

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Identifiers

PMID: 20347630
DOI: 10.1016/j.vaccine.2010.03.028
PMCID: PMC2895808

Genes

ERAP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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