Article
Induction of partial protection against infection with Toxoplasma gondii genotype II by DNA vaccination with recombinant chimeric tachyzoite antigens.
Vaccine - 21 Apr 2009
Rosenberg Carina, De Craeye Stéphane, Jongert Erik, Gargano Nicola, Beghetto Elisa, Del Porto Paola, Vorup-Jensen Thomas, Petersen Eskild
Abstract excerpt
Infection with the obligate intracellular parasite Toxoplasma gondii is a significant source of parasitic infections worldwide. In adults, infections may often lead to severe retinochoroiditis. Infection of the foetus causes abortion or congenital pathology that may lead to neurological complications. Although several strategies have been suggested for making a vaccine, none is currently available. Here, we...
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