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Article

Identification of Toxoplasma gondii antigenic proteins using an in vivo approach and in silico investigation of their polymorphism.

Microbiology spectrum - 6 May 2025

Denis J, Gommenginger C, Beal L, Cimon B, Deleplancque A S, Fricker Hidalgo H, L'Ollivier C, Paris L, Pelloux H, Pomares C, Houze S, Pfaff A W, Villena I, Villard O

Abstract excerpt

Toxoplasma gondii is a pathogen characterized by a large variety of strains whose virulence and clinical severity are likely linked to their genotype. Currently, the strains are genotyped using restriction fragment length polymorphism, multilocus sequence typing, and microsatellite markers. This typing requires the strain's DNA, which is difficult to obtain. A serotyping test could overcome the constraints of...

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Identifiers

PMID: 40135885
DOI: 10.1128/spectrum.02040-24
PMCID: PMC12054087

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SAG

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