Article
Analysis of GNAS mutations in cemento-ossifying fibromas and cemento-osseous dysplasias of the jaws.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics - 1 May 2010
Patel Milan M, Wilkey Jonathan F, Abdelsayed Rafik, D'Silva Nisha J, Malchoff Carl, Mallya Sanjay M
Abstract excerpt
OBJECTIVES: It is well established that fibrous dysplasia (FD) is caused by mutations of the Arg(201) codon of the GNAS gene. However, the role of GNAS mutation in the pathogenesis of cement-osseous dysplasias (COD) and cemento-ossifying fibromas (COF) is not fully known. In this study, we examined COD and COF for mutations at the Arg(201) codon of the GNAS gene. STUDY DESIGN: The study sample included...
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