Article
Hereditary Causes of Disturbed Iron Homeostasis in the Central Nervous System
1 Mar 2004
Abstract excerpt
Iron is essential for oxidation-reduction catalysis and bioenergetics; however, unless appropriately shielded, this metal plays a crucial role in the formation of toxic oxygen radicals that can attack all biological molecules. Organisms are equipped with specific proteins designed for iron acquisition, export and transport, and storage, as well as with sophisticated mechanisms that maintain the intracellular...
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