Article
FoxM1B regulates NEDD4-1 expression, leading to cellular transformation and full malignant phenotype in immortalized human astrocytes.
Cancer research - 1 Apr 2010
Dai Bingbing, Pieper Russell O, Li Dawei, Wei Ping, Liu Mingguang, Woo Shiao Y, Aldape Kenneth D, Sawaya Raymond, Xie Keping, Huang Suyun
Abstract excerpt
Our recent studies have shown that the FoxM1B transcription factor is overexpressed in human glioma tissues and that the level of its expression correlates directly with glioma grade. However, whether FoxM1B plays a role in the early development of glioma (i.e., in transformation) is unknown. In...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
