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Article

Genotype-based risk and pharmacogenetic sampling in clinical trials.

Journal of biopharmaceutical statistics - 1 Mar 2010

Schork Nicholas J, Topol Eric J

Abstract excerpt

A number of recent genome-wide association (GWA) studies have identified unequivocal statistical associations between inherited genetic variations, mostly single-nucleotide polymorphisms (SNPs), and common complex diseases such as diabetes, cardiovascular disease, and obesity. Genotyping individuals for these variations has the potential to help redefine how pharmacologic agents undergo clinical development. By...

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Identifiers

PMID: 20309761
DOI: 10.1080/10543400903572779
PMCID: PMC2892229

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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