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Article

An improved ivermectin-activated chloride channel receptor for inhibiting electrical activity in defined neuronal populations.

The Journal of biological chemistry - 14 May 2010

Lynagh Timothy, Lynch Joseph W

Abstract excerpt

The ability to silence the electrical activity of defined neuronal populations in vivo is dramatically advancing our understanding of brain function. This technology may eventually be useful clinically for treating a variety of neuropathological disorders caused by excessive neuronal activity. Several neuronal silencing methods have been developed, with the bacterial light-activated halorhodopsin and the...

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Identifiers

PMID: 20308070
DOI: 10.1074/jbc.M110.107789
PMCID: PMC2865309

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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