Article
Genetic characteristics, coreceptor usage potential and evolution of Nigerian HIV-1 subtype G and CRF02_AG isolates.
PloS one - 14 Mar 2011
Ajoge Hannah O, Gordon Michelle L, de Oliveira Tulio, Green Taryn N, Ibrahim Sani, Shittu Oladapo S, Olonitola Stephen O, Ahmad Aliyu A, Ndung'u Thumbi
Abstract excerpt
HIV-1 CRF02_AG and subtype G (HIV-1G) account for most HIV infections in Nigeria, but their evolutionary trends have not been well documented. To better elucidate the dynamics of the epidemic in Nigeria we characterised the gag and env genes of North-Central Nigerian HIV-1 isolates from pregnant women. Of 28 samples sequenced in both genes, the predominant clades were CRF02_AG (39%) and HIV-1G (32%). Higher...
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