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Article

Association of estrogen and aromatase gene polymorphisms with systemic lupus erythematosus.

Lupus - 1 May 2010

Wang J, Nuite M, McAlindon T E

Abstract excerpt

Experimental and animal studies suggested that estrogens play an important role in the development of systemic lupus erythematosus (SLE) through a variety of mechanisms involved in the regulation of the immune system. The objective of this study was to investigate the association between genetic variations in estrogen metabolic pathway genes, including estrogen receptor alpha (ESR1), estrogen receptor beta...

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Source

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Identifiers

PMID: 20305046
DOI: 10.1177/0961203309359517
PMCID: PMC3653634

Genes

ESR1
ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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