Article
Association of the oestrogen receptor alpha gene polymorphisms with disease onset in systemic lupus erythematosus.
Annals of the rheumatic diseases - 1 Oct 2004
Lee Y J, Shin K S, Kang S W, Lee C K, Yoo B, Cha H S, Koh E M, Yoon S J, Lee J
Abstract excerpt
OBJECTIVE: To evaluate the genetic influence of PvuII and XbaI polymorphisms of oestrogen receptor alpha (ORalpha) in patients with systemic lupus erythematosus (SLE) in Korea. METHODS: Genomic DNA from 268 female controls and 137 female SLE patients (41 childhood onset and 96 adult onset) were analysed using PvuII and XbaI restriction fragment length polymorphism. Comparison of the frequencies of alleles and...
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