Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Type 1 von Willebrand disease due to reduced von Willebrand factor synthesis and/or survival: observations from a case series.

Translational research : the journal of laboratory and clinical medicine - 1 Apr 2010

Casonato Alessandra, Gallinaro Lisa, Cattini Maria Grazia, Sartorello Francesca, Pontara Elena, Padrini Roberto, Bertomoro Antonella, Daidone Viviana, Pagnan Antonio

Abstract excerpt

It may be difficult to diagnose type 1 von Willebrand disease (VWD) because of its heterogeneous and sometimes elusive nature. To evaluate the contribution of a shorter von Willebrand factor (VWF) survival in modulating VWD phenotype, the VWF half-life was assessed in 45 type 1 VWD patients using a 24-h 1-desamino-8-d-arginine vasopressin (DDAVP) test. A shorter VWF survival was observed in patients with C1130F...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ABO Blood-Group System
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Deamino Arginine Vasopressin

Share to Half-Life

Share to Hemostasis

Share to Mutation

Share to Peptides

Share to von Willebrand Factor

Source

Identifiers

PMID: 20303469
DOI: 10.1016/j.trsl.2009.12.003

Genes

VWF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Type 1 von Willebrand disease due to reduced von Willebrand factor synthesis and/or survival: observations from a case series.PMID 20303469Read ↗

Von Willebrand factor propeptide makes it easy to identify the shorter Von Willebrand factor survival in patients with type 1 and type Vicenza von Willebrand disease.Semantic proximity Read ↗

Assay of the von Willebrand factor (VWF) propeptide to identify patients with type 1 von Willebrand disease with decreased VWF survival.Semantic proximity Read ↗

Reduced survival of type 2B von Willebrand factor, irrespective of large multimer representation or thrombocytopenia.Semantic proximity Read ↗

Survival of von Willebrand factor released following DDAVP in a type 1 von Willebrand disease cohort: influence of glycosylation, proteolysis and gene mutations.Semantic proximity Read ↗

Identification of type 1 von Willebrand disease patients with reduced von Willebrand factor survival by assay of the VWF propeptide in the European study: molecular and clinical markers for the diagnosis and management of type 1 VWD (MCMDM-1VWD).Semantic proximity Read ↗

Reduced von Willebrand factor survival in von Willebrand disease: pathophysiologic and clinical relevance.Semantic proximity Read ↗

Reduced von Willebrand factor survival in type Vicenza von Willebrand disease.Semantic proximity Read ↗

Clearance of von Willebrand factorSemantic proximity Read ↗

VWF propeptide and ratios between VWF, VWF propeptide, and FVIII in the characterization of type 1 von Willebrand disease.Semantic proximity Read ↗

A new variant of von Willebrand's disease (type I Padua): doublet-organized plasma von Willebrand factor oligomers in the presence of all size multimers.Semantic proximity Read ↗

von Willebrand factor and factor VIII levels after desmopressin are associated with bleeding phenotype in type 1 VWD.Semantic proximity Read ↗

von Willebrand disease and aging: an evolving phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.