Article
A variant in LIN28B is associated with 2D:4D finger-length ratio, a putative retrospective biomarker of prenatal testosterone exposure.
American journal of human genetics - 9 Apr 2010
Medland Sarah E, Zayats Tetyana, Glaser Beate, Nyholt Dale R, Gordon Scott D, Wright Margaret J, Montgomery Grant W, Campbell Megan J, Henders Anjali K, Timpson Nicholas J, Peltonen Leena, Wolke Dieter, Ring Susan M, Deloukas Panos, Martin Nicholas G, Smith George Davey, Evans David M
Abstract excerpt
The ratio of the lengths of an individual's second to fourth digit (2D:4D) is commonly used as a noninvasive retrospective biomarker for prenatal androgen exposure. In order to identify the genetic determinants of 2D:4D, we applied a genome-wide association approach to 1507 11-year-old children from the Avon Longitudinal Study of Parents and Children (ALSPAC) in whom 2D:4D ratio had been measured, as well as a...
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