Article
Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero.
Human molecular genetics - 1 Jun 2018
Warrington Nicole M, Shevroja Enisa, Hemani Gibran, Hysi Pirro G, Jiang Yunxuan, Auton Adam, Boer Cindy G, Mangino Massimo, Wang Carol A, Kemp John P, McMahon George, Medina-Gomez Carolina, Hickey Martha, Trajanoska Katerina, Wolke Dieter, Ikram M Arfan, Montgomery Grant W, Felix Janine F, Wright Margaret J, Mackey David A, Jaddoe Vincent W, Martin Nicholas G, Tung Joyce Y, Davey Smith George, Pennell Craig E, Spector Tim D, van Meurs Joyce, Rivadeneira Fernando, Medland Sarah E, Evans David M
Abstract excerpt
The ratio of the length of the index finger to that of the ring finger (2D:4D) is sexually dimorphic and is commonly used as a non-invasive biomarker of prenatal androgen exposure. Most association studies of 2D:4D ratio with a diverse range of sex-specific traits have typically involved small sample sizes and have been difficult to replicate, raising questions around the utility and precise meaning of the...
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