Article
Conserved patterns of sequence diversification provide insight into the evolution of two-component systems in Enterobacteriaceae.
Microbial genomics - 1 Mar 2024
Barretto Luke A F, Van Patryc-Khang T, Fowler Casey C
Abstract excerpt
Two-component regulatory systems (TCSs) are a major mechanism used by bacteria to sense and respond to their environments. Many of the same TCSs are used by biologically diverse organisms with different regulatory needs, suggesting that the functions of TCS must evolve. To explore this topic, we analysed the amino acid sequence divergence patterns of a large set of broadly conserved TCS across different branches...
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