Human Breast Cancer Cell Lines Co-Express Neuronal, Epithelial, and Melanocytic Differentiation Markers In Vitro and In Vivo

Abstract excerpt

Differentiation programs are aberrant in cancer cells allowing them to express differentiation markers in addition to their tissue of origin. In the present study, we demonstrate the multi-lineage differentiation potential of breast cancer cell lines to express multiple neuronal/glial lineage-specific markers as well as mammary epithelial and melanocytic-specific markers. Multilineage expression was detected in...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Axon Guidance and Neuronal Signaling
• Share to Cancer Cells and Metastasis
• Share to Wnt/β-catenin signaling in development and cancer