Functional rs20417 SNP (-765G>C) of cyclooxygenase-2 gene does not predict the risk of recurrence of ischemic events in coronary patients: results of a 7-year prospective study.

doi:10.1159/000298880

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Article

Functional rs20417 SNP (-765G>C) of cyclooxygenase-2 gene does not predict the risk of recurrence of ischemic events in coronary patients: results of a 7-year prospective study.

Cardiology - 1 Jan 2010

Montali Anna, Barillà Francesco, Tanzilli Gaetano, Vestri Annarita, Fraioli Antonio, Gaudio Carlo, Martino Francesco, Mezzetti Andrea, Cipollone Francesco, Arca Marcello

Abstract excerpt

OBJECTIVES: The -765G>C variation (rs20417 SNP) in the promoter of cyclooxygenase-2 (COX-2) gene has been demonstrated to lower COX-2 enzyme activity in the vasculature, thus affecting atherosclerotic plaque growth and stability. Therefore, this genetic variant may be a candidate influencing the...

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PMID: 20299798
DOI: 10.1159/000298880

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20299798-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

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