Article
Loss of heterozygosis on IFN-alpha locus is a prognostic indicator of bacillus Calmette-Guerin response for nonmuscle invasive bladder cancer.
The Journal of urology - 1 May 2010
Cai Tommaso, Nesi Gabriella, Dal Canto Maurizio, Tinacci Galliano, Mondaini Nicola, Piazzini Mauro, Geppetti Pierangelo, Bartoletti Riccardo
Abstract excerpt
PURPOSE: We evaluated the role of loss of heterozygosity on the interferon-alpha locus to predict the response to bacillus Calmette-Guerin therapy in patients with nonmuscle invasive bladder cancer. MATERIALS AND METHODS: A total of 117 consecutive patients were selected, including 77 with nonmuscle invasive bladder cancer and 40 controls. Loss of heterozygosity on the interferon-alpha locus (chromosome 9p21) was...
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