Article
Effects of interleukin-6 on cellular function in UMR-106-01 osteoblastlike cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Feb 1991
Fang M A, Hahn T J
Abstract excerpt
High levels of interleukin-6 (IL-6) have been detected in synovial fluid from patients with inflammatory arthropathies associated with local bone resorption, suggesting a role for IL-6 as a local regulator of bone resorption and remodeling. In the present study we examined the effects of IL-6 on [3H]thymidine ([3H]TdR) incorporation, collagen synthesis, and alkaline phosphatase activity in UMR-106-01 rat...
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