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Article

Effects of genistein on expression of bone markers during MC3T3-E1 osteoblastic cell differentiation.

The Journal of nutritional biochemistry - 1 Jun 2003

Chen Xiaowei, Garner Sanford C, Quarles L Darryl, Anderson John J B

Abstract excerpt

In this in vitro study, the hypothesis that the beneficial effects of dietary genistein on bone are through the modulation of the bone marker synthesis by osteoblastic MC3T3-E1 cells was tested, and the possible roles of estrogen receptors in the actions of genistein on osteoblastic cells were also examined. Interleukin-6 production was decreased 40% to 60% in osteoblastic cells treated with genistein from either...

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PMID: 12873716
DOI: 10.1016/s0955-2863(03)00056-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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