Lipid interaction of diphtheria toxin and mutants. A study with phospholipid and protein monolayers.

doi:10.1111/j.1432-1033.1991.tb15935.x

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Article

Lipid interaction of diphtheria toxin and mutants. A study with phospholipid and protein monolayers.

European journal of biochemistry - 23 Apr 1991

Demel R, Schiavo G, de Kruijff B, Montecucco C

Abstract excerpt

To study the structural change of diphtheria toxin (DT) induced by low pH and its influence on the interaction with membrane lipids, protein and lipid monolayers were formed and characterized. DT at neutral and acidic pH forms stable monolayers, whose surface-pressure-increase curves allow an est...

Topics

Diphtheria Toxin
Hydrogen-Ion Concentration
Membrane Lipids
Membrane Proteins
Mutation
Phospholipids

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