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Article

Analysis of Polo-like kinase Cdc5 in the meiosis recombination checkpoint.

Cell cycle (Georgetown, Tex.) - 15 Mar 2010

Iacovella Maria G, Daly Catherine N, Kelly Jamie-Sioux, Michielsen Adriana J, Clyne Rosemary K

Abstract excerpt

In meiosis, accumulation of recombination intermediates or defects in chromosome synapsis trigger checkpoint-mediated arrest in prophase I. Such 'checkpoints' are important surveillance mechanisms that ensure temporal dependence of cell cycle events. The budding yeast Polo-like kinase, Cdc5, has been identified as a key regulator of the meiosis I chromosome segregation pattern. Here we have analysed the role of...

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PMID: 20237423
DOI: 10.4161/cc.9.6.11068

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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