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Article

MFSD2A is a novel lung tumor suppressor gene modulating cell cycle and matrix attachment

17 Mar 2010

Abstract excerpt

BACKGROUND: MFSD2A (major facilitator superfamily domain containing 2) gene maps on chromosome 1p34 within a linkage disequilibrium block containing genetic elements associated with progression of lung cancer. RESULTS: Here we show that MFSD2A expression is strongly downregulated in non-small cell lung cancer cell lines of different histotypes and in primary lung adenocarcinomas. Experimental modulation of MFSD2A...

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PMID: 20236515
DOI: 10.1186/1476-4598-9-62

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