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Article

Is canalization more than just a beautiful idea?

Genome biology - 1 Jan 2010

Sato Kaoru, Siomi Haruhiko

Abstract excerpt

The heat-shock protein 90 (Hsp90) is currently thought to buffer eukaryotic cells against perturbations caused by pre-existing cryptic genetic variation. A new study suggests that the buffering function of Hsp90 could instead be due to its repression of de novo transposon-mediated mutagenesis.

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Identifiers

PMID: 20236474
DOI: 10.1186/gb-2010-11-3-109
PMCID: PMC2864559

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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