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Article

Assessing the influence of adjacent gene orientation on the evolution of gene upstream regions in Arabidopsis thaliana.

Genetics - 1 Jun 2010

He Fei, Chen Wei-Hua, Collins Sinéad, Acquisti Claudia, Goebel Ulrike, Ramos-Onsins Sebastian, Lercher Martin J, de Meaux Juliette

Abstract excerpt

The orientation of flanking genes may influence the evolution of intergenic regions in which cis-regulatory elements are likely to be located: divergently transcribed genes share their 5' regions, resulting either in smaller "private" spaces or in overlapping regulatory elements. Thus, upstream sequences of divergently transcribed genes (bi-directional upstream regions, or URs) may be more constrained than those...

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Identifiers

PMID: 20233855
DOI: 10.1534/genetics.110.114629
PMCID: PMC2881148

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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