Article
Epistatic and allelic interactions control expression of ribosomal RNA gene clusters in Arabidopsis thaliana.
Genome biology - 3 May 2017
Rabanal Fernando A, Mandáková Terezie, Soto-Jiménez Luz M, Greenhalgh Robert, Parrott David L, Lutzmayer Stefan, Steffen Joshua G, Nizhynska Viktoria, Mott Richard, Lysak Martin A, Clark Richard M, Nordborg Magnus
Abstract excerpt
BACKGROUND: Ribosomal RNA (rRNA) accounts for the majority of the RNA in eukaryotic cells, and is encoded by hundreds to thousands of nearly identical gene copies, only a subset of which are active at any given time. In Arabidopsis thaliana, 45S rRNA genes are found in two large ribosomal DNA (rDNA) clusters and little is known about the contribution of each to the overall transcription pattern in the species....
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