Article
Association of the MCP-1 -2518 A/G polymorphism and no association of its receptor CCR2 -64 V/I polymorphism with lupus nephritis.
The Journal of rheumatology - 1 Apr 2010
Malafronte Patricia, Vieira Jose Mauro, Pereira Alexandre Carlos, Krieger Jose Eduardo, Barros Rui Toledo, Woronik Viktoria
Abstract excerpt
OBJECTIVE: To evaluate whether the A/G polymorphism at position -2518 in the regulatory region of the monocyte chemoattractant protein-1 (MCP-1) or the V/I polymorphism at position -64 of the receptor, CCR2, are associated with lupus nephritis (LN) or any clinical characteristics of the disease or with renal survival in a patient population. METHODS: We selected 197 patients with lupus nephritis and 220 matched...
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