Article
Enhanced generation of megakaryocytes from umbilical cord blood-derived CD34(+) cells expanded in the presence of two nutraceuticals, docosahexanoic acid and arachidonic acid, as supplements to the cytokine-containing medium.
Cytotherapy - 1 Jan 2011
Siddiqui Nikhat Firdaus A, Shabrani Namrata C, Kale Vaijayanti P, Limaye Lalita S
Abstract excerpt
BACKGROUND AIMS: Ex vivo generation of megakaryocytes (MK) from hematopoietic stem cells (HSC) is important for both basic research, to understand the mechanism of platelet biogenesis, and clinical infusions, for rapid platelet recovery in thrombocytopenic patients. We investigated the role of tw...
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