Article
Radionuclide angiography with technetium-99m in vivo labeled erythrocytes does not lead to induction of mutations in the HPRT gene of human T-lymphocytes.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine - 1 May 1991
van Dam F J, Camps J A, Woldring V M, Natarajan A T, van der Wall E E, Zwinderman A H, Lohman P H, Pauwels E K, Tates A D
Abstract excerpt
Mutant frequencies were measured in T-lymphocytes of patients undergoing radionuclide angiography with erythrocytes labeled in vivo with technetium-99m. Blood from 13 patients was sampled before and after (8-120 days) an injection with 750 MBq technetium-99m. Frequencies of HPRT- mutants were mea...
Topics
- Adult
- Aged
- Erythrocytes
- Female
- Gated Blood-Pool Imaging
- Humans
- Hypoxanthine Phosphoribosyltransferase
- Male
- Middle Aged
- Mutation
- Radiation Genetics
- T-Lymphocytes
- Technetium