Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nuclear medicine patients do not have higher mutant frequencies after exposure to thallium-201.

Mutation research - 1 Jan 1991

Bachand M, Seifert A M, Messing K

Abstract excerpt

The HPRT-lymphocyte clonal assay has been used to detect mutants induced in vivo in humans. This method has previously detected a rise in mutant frequency among nuclear medicine patients following exposure to technetium-99m, at a dose corresponding in theory to 5.1 mGy. In the present study, nuclear medicine patients were sampled before and after exposure to thallium-201, corresponding to a whole-body dose of 4.2...

Topics

Adult
Animals
Female
Humans
Hypoxanthine Phosphoribosyltransferase
Male
Middle Aged
Mutagenicity Tests
Mutation
Thallium Radioisotopes

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1986278
DOI: 10.1016/0165-7992(91)90097-n

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1986278-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Nuclear medicine patients do not have higher mutant frequencies after exposure to thallium-201.PMID 1986278Read ↗

Genotoxic and mutagenic effects of the diagnostic use of thallium-201 in nuclear medicine.Semantic proximity Read ↗

Nature of mutation in the human hprt gene following in vivo exposure to ionizing radiation of cesium-137.Semantic proximity Read ↗

Radionuclide angiography with technetium-99m in vivo labeled erythrocytes does not lead to induction of mutations in the HPRT gene of human T-lymphocytes.Semantic proximity Read ↗

Reduced proliferation rate of hypoxanthine-phosphoribosyl transferase mutant human T-lymphocytes in vitro.Semantic proximity Read ↗

Thioguanine-resistant mutant frequency in T-lymphocytes from a healthy human population.Semantic proximity Read ↗

Mutant frequency at the HPRT locus in peripheral blood T-lymphocytes of atomic bomb survivors.Semantic proximity Read ↗

Use of the clonal assay for the measurement of frequencies of HPRT mutants in T-lymphocytes from five control populations.Semantic proximity Read ↗

Dose response for T-cell receptor (TCR) mutants in patients repeatedly treated with 131I for thyroid cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.