Article
Genotoxic and mutagenic effects of the diagnostic use of thallium-201 in nuclear medicine.
Mutation research - 1 Jul 1991
Kelsey K T, Donohoe K J, Baxter B, Memisoglu A, Little J B, Caggana M, Liber H L
Abstract excerpt
In order to investigate possible mutagenic effects of in vivo exposure to low levels of ionizing radiation used in nuclear medicine, we have examined the hypoxanthine guanine phosphoribosyl transferase (hprt) mutant fraction (MF) and chromosome aberration (CA) frequency in 24 nuclear medicine patients before and after injection of thallium-201. The mean MF of the thallium-201-exposed cohort was 5.2 +/- 4.4 x...
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