Article
A polymorphism of microRNA196a genome region was associated with decreased risk of glioma in Chinese population.
Journal of cancer research and clinical oncology - 1 Dec 2010
Dou Tonghai, Wu Qihan, Chen Xin, Ribas Judit, Ni Xiaohua, Tang Cheng, Huang Fengping, Zhou Liangfu, Lu Daru
Abstract excerpt
MicroRNAs (miRNAs) are small non-coding RNAs that play important roles in regulation of eukaryotic gene expression. Aberrant expression and structural alternation of miRNAs are considered to participate in tumorigenesis and cancer development. Recently, different genotypes of miR-196a polymorphisms (SNP, rs11614913) were found to be associated with the survival of patients with lung cancer and increased risk of...
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