Article
Associations of miR‑146aC>G, miR‑149C>T, miR‑196a2C>T and miR‑499A>G polymorphisms with brain tumors.
Oncology reports - 1 Sept 2018
Lim Jaejoon, Kim Jung Oh, Park Han Sung, Han In Bo, Kwack Kyubum, Kim Nam Keun, Cho Kyunggi
Abstract excerpt
MicroRNAs (miRNAs/miRs) are short, non‑coding RNAs that are implicated in tumorigenesis, functioning as tumor suppressors and oncogenes. However, the clinical significance of miRNA expression profiles for brain tumors remains unclear. Therefore, the present study was designed to investigate the associations between miRNA genetic variants and brain tumor risk. A total 362 participants were recruited, including...
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