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Article

FMR1 repeat sizes in the gray zone and high end of the normal range are associated with premature ovarian failure.

Human genetics - 1 Aug 2005

Bretherick Karla L, Fluker Margo R, Robinson Wendy P

Abstract excerpt

Premature ovarian failure (POF) is the occurrence of menopause before the age of 40 and affects 1% of the female population. Whereas the etiology of POF is largely unexplained, FMR1 premutation carriers are known to be at increased risk of POF compared with the general population. The FMR1 premutation alleles have 55-200 copies of a CGG repeat in the 5' untranslated region of the FMR1 gene. However, functional...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16078053
DOI: 10.1007/s00439-005-1326-8

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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FMR1 repeat sizes in the gray zone and high end of the normal range are associated with premature ovarian failure.PMID 16078053Read ↗

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