Article
A functional polymorphism in the disrupted-in schizophrenia 1 gene is associated with chronic fatigue syndrome.
Life sciences - 8 May 2010
Fukuda Sanae, Hashimoto Ryota, Ohi Kazutaka, Yamaguti Kouzi, Nakatomi Yasuhito, Yasuda Yuka, Kamino Kouzin, Takeda Masatoshi, Tajima Seiki, Kuratsune Hirohiko, Nishizawa Yoshiki, Watanabe Yasuyoshi
Abstract excerpt
AIMS: Disrupted-in schizophrenia 1 (DISC1), identified in a pedigree with a familial psychosis with the chromosome translocation (1:11), is a putative susceptibility gene for psychoses such as schizophrenia and major depressive disorder (MDD). Patients with chronic fatigue syndrome (CFS) report having continuous severe fatigue and many overlapping symptoms with MDD; however, the mechanism and effective treatment...
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