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Article

Myosin individualized: single nucleotide polymorphisms in energy transduction.

BMC genomics - 15 Mar 2010

Burghardt Thomas P, Neff Kevin L, Wieben Eric D, Ajtai Katalin

Abstract excerpt

BACKGROUND: Myosin performs ATP free energy transduction into mechanical work in the motor domain of the myosin heavy chain (MHC). Energy transduction is the definitive systemic feature of the myosin motor performed by coordinating in a time ordered sequence: ATP hydrolysis at the active site, actin affinity modulation at the actin binding site, and the lever-arm rotation of the power stroke. These functions are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20226094
DOI: 10.1186/1471-2164-11-172
PMCID: PMC2848645

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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