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Article

Bioinformatics assessment of beta-myosin mutations reveals myosin's high sensitivity to mutations.

Trends in cardiovascular medicine - 1 May 2008

Buvoli Massimo, Hamady Micah, Leinwand Leslie A, Knight Rob

Abstract excerpt

More than 200 mutations in the beta-myosin gene (MYH7) that cause clinically distinct cardiac and/or skeletal myopathies have been reported, but to date, no comprehensive statistical analysis of these mutations has been performed. As a part of this review, we developed a new interactive database and research tool called MyoMAPR (Myopathic Mutation Analysis Profiler and Repository). We report that the distribution...

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Share to Cardiac Myosins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Databases, Genetic

Share to Genomics

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Share to Myosin Heavy Chains

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Source

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Identifiers

PMID: 18555187
DOI: 10.1016/j.tcm.2008.04.001
PMCID: PMC2587080

Genes

MYH7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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