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Article

Analysis of human small nucleolar RNAs (snoRNA) and the development of snoRNA modulator of gene expression vectors.

Molecular biology of the cell - 1 May 2010

Ono Motoharu, Yamada Kayo, Avolio Fabio, Scott Michelle S, van Koningsbruggen Silvana, Barton Geoffrey J, Lamond Angus I

Abstract excerpt

Human small nucleolar RNAs (snoRNAs) that copurify with nucleoli isolated from HeLa cells have been characterized. Novel fibrillarin-associated snoRNAs were detected that allowed the creation of a new vector system for the targeted knockdown of one or more genes in mammalian cells. The snoMEN (sn...

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Identifiers

PMID: 20219969
DOI: 10.1091/mbc.e10-01-0078
PMCID: PMC2861615

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20219969-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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