Article
ADH1B*2 allele is protective against alcoholism but not chronic liver disease in the Hungarian population.
Addiction (Abingdon, England) - 1 May 2010
Toth Reka, Pocsai Zsuzsa, Fiatal Szilvia, Szeles Gyorgy, Kardos Laszlo, Petrovski Beata, McKee Martin, Adany Roza
Abstract excerpt
BACKGROUND: Standardized death rates from chronic liver diseases (CLDs) in Hungary are much higher than the European Union average. Carrying the alcohol dehydrogenase 1B 48His allele (rs1229984 or ADH1B*2) could decrease the risk of alcoholism, but with persistent drinking may confer a greater risk of CLDs. The aim of this study was to assess the prevalence of this polymorphism in the Hungarian population and its...
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