Article
[Evaluating the biological efficacy of clopidogrel: genotype or phenotype?].
Revue medicale suisse - 10 Feb 2010
Fontana Pierre, Bonvini Robert F, Roffi Marco, Boehlen Françoise, Reber Guido, de Moerloose Philippe, Reny Jean-Luc
Abstract excerpt
Clopidogrel has a known biological variability that has been consistently associated with recurrence of coronary ischemic events in clinical studies. Among the tests that are currently available, quantification of the phosphorylation status of the vasodilator phosphoprotein (VASP assay) is probably the most specific assay to evaluate the inhibition of the P2Y12 receptor by clopidogrel. A genetic polymorphism of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
