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Article

Transcobalamin C776G genotype modifies the association between vitamin B12 and homocysteine in older Hispanics.

European journal of clinical nutrition - 1 May 2010

Garrod M G, Allen L H, Haan M N, Green R, Miller J W

Abstract excerpt

BACKGROUND/OBJECTIVES: A common polymorphism, C776G, in the plasma B12 transport protein transcobalamin (TC), encodes for either proline or arginine at codon 259. This polymorphism may affect the affinity of TC for B12 and subsequent delivery of B12 to tissues. SUBJECTS/METHODS: TC genotype and its associations with indicators of B12 status, including total B12, holotranscobalamin (holoTC), methylmalonic acid and...

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Identifiers

PMID: 20216556
DOI: 10.1038/ejcn.2010.20
PMCID: PMC2864787

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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