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Article

Transcobalamin II 775G>C polymorphism and indices of vitamin B12 status in healthy older adults.

Blood - 15 Jul 2002

Miller Joshua W, Ramos Marisa I, Garrod Marjorie G, Flynn Margaret A, Green Ralph

Abstract excerpt

A common polymorphism (775G>C) in the vitamin B12 transport protein, transcobalamin II (TCII), has been identified in which proline replaces arginine at codon 259. We determined the influence of TCII genotype on indices of B12 status, including total serum B12, the amount of B12 bound to TCII (holoTCII), methylmalonic acid, and homocysteine, in 128 healthy older adults (ages 40-88 years). Mean total B12 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12091374
DOI: 10.1182/blood-2002-01-0209

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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