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Article

Differential effects of sumoylation on transcription and alternative splicing by transcription elongation regulator 1 (TCERG1).

The Journal of biological chemistry - 14 May 2010

Sánchez-Álvarez Miguel, Montes Marta, Sánchez-Hernández Noemí, Hernández-Munain Cristina, Suñé Carlos

Abstract excerpt

Modification of proteins by small ubiquitin-like modifier (SUMO) is emerging as an important control of transcription and RNA processing. The human factor TCERG1 (also known as CA150) participates in transcriptional elongation and alternative splicing of pre-mRNAs. Here, we report that SUMO family proteins modify TCERG1. Furthermore, TCERG1 binds to the E2 SUMO-conjugating enzyme Ubc9. Two lysines (Lys-503 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20215116
DOI: 10.1074/jbc.M109.063750
PMCID: PMC2865347

Genes

TCERG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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