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Article

Genetic polymorphisms on the factor V gene in women with recurrent miscarriage and acquired APCR.

Human reproduction (Oxford, England) - 1 Sept 2007

Dawood Feroza, Mountford Roger, Farquharson Roy, Quenby Siobhan

Abstract excerpt

BACKGROUND: Recurrent miscarriage (RM) has been associated with the thrombophilia, activated protein C resistance (APCR). The factor V Leiden mutation located on the B domain of the factor V gene, causes 95% of APCR and since the B domain is pivotal to APCR, it seemed plausible that other mutations or polymorphisms affecting this active domain may instigate acquired APCR. The objective of this study was to...

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Identifiers

PMID: 17640947
DOI: 10.1093/humrep/dem210

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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