Article
Factor V Leiden is associated with pre-eclampsia but not with fetal growth restriction: a genetic association study and meta-analysis.
Journal of thrombosis and haemostasis : JTH - 1 Nov 2008
Dudding T, Heron J, Thakkinstian A, Nurk E, Golding J, Pembrey M, Ring S M, Attia J, Scott R J
Abstract excerpt
BACKGROUND: Adverse pregnancy outcomes have been related to environmental and/or genetic factors. Of interest are genes associated with the clotting system as any perturbation in the balance of thrombotic and thrombolytic cascades could affect the placental circulation and hence the viability of the developing fetus. Several previous reports using relatively small numbers of cases and controls have suggested that...
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