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Article

Mutations in Keap1 are a potential prognostic factor in resected non-small cell lung cancer.

Journal of surgical oncology - 1 May 2010

Takahashi Tsuyoshi, Sonobe Makoto, Menju Toshi, Nakayama Ei, Mino Nobuya, Iwakiri Shotaro, Nagai Shinjiro, Sato Kiyoshi, Miyahara Ryo, Okubo Kenichi, Hirata Toshiki, Date Hiroshi, Wada Hiromi

Abstract excerpt

BACKGROUND: Mutations in Kelch-like ECH-associated protein 1 (Keap1) have been reported to protect tumor cells from chemotherapeutic agents. However, their prognostic significance in nonsmall cell lung cancer (NSCLC) is still unclear. In this study, we examined the effect of Keap1 gene mutations on survival and disease-free interval using resected primary NSCLC tissue. METHODS: We retrospectively analyzed the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20213688
DOI: 10.1002/jso.21520

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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