Article
DNA methylation and carcinogenesis of PRDM5 in cervical cancer.
Journal of cancer research and clinical oncology - 1 Dec 2010
Cheng Hai-Yan, Chen Xiu-Wei, Cheng Li, Liu Yun-Duo, Lou Ge
Abstract excerpt
OBJECTIVE: PR (PRDI-BF1 and RIZ) domain proteins (PRDM) are a subfamily of the kruppel-like zinc finger gene products and play key roles during cell differentiation and malignant transformation. PRDM5 (PR domain containing 5 PFM2) is a new PR-domain-containing gene. The purpose of the present study was to examine the expression of PRDM5 and evaluate its carcinogenesis in cervical cancer. The relationship between...
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